Description:
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PT73 E. coli (THR) consists of a
genetically modified strain of Escherichia coli K12, named strain TK7.
Strain TK7 consists of recipient strain TKIIHdeltaPPC and the plasmid pK1:APT:AB which contains 5 functional elements derived from E. coli K12 related to amino acid metabolism and the selection marker nptI providing resistance to kanamycin.
The purpose of the genetic modification is to increase the enzymatic activities of the threonine biosynthetic pathway and of the general metabolism pathway.
The strain TK7 is used for the production of L-threonine by fermentation of substrates of agricultural origin.
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Links regarding to this GMO:
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Transformation / Modification technique:
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