Description:
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DP51291 maize was genetically modified by SSI (site-specific integration) to express the IPD072Aa protein for control of susceptible maize rootworm (CRW) pests, the phosphinothricin acetyltransferase (PAT) protein for tolerance to glufosinate herbicide, and the phosphomannose isomerase (PMI) protein that was used as a
selectable marker. The inserted region contains three gene cassettes:
the ipd072Aa gene cassette (CS-ipd072Aa-PSECL) encoding for the IPD072Aa protein, which confers protection against certain coleopteran pests,
the pat gene cassette (CS-pat-STRVR) from Streptomyces viridochromogenes encoding for the PAT enzyme, which confers tolerance to phosphinothricin (a.k.a. glufosinate),
the pmi gene cassette (CS- pmi-ECOLX) from Escherichia coli encoding for the PMI protein in plants, which serves as selectable marker
and allows plant tissue growth with mannose as the carbon source.
Molecular characterization analyses demonstrated that the introduced genes are integrated at a single locus, stably inherited across multiple generations, and segregate according to Mendel’s
law of genetics.
Source:
EFSA document: Application submitted under regulation (EC) No 1829/2003: Part VII Summary - DP51291
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Links regarding to this GMO:
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FSANZ https://www.foodstandards.gov.au/code/applications/Pages/A1270---Food-derived-from-herbicide-tolerant-and-insect-protected-corn-line-DP51291.aspx,
EFSA public summary https://open.efsa.europa.eu/dossier/GMFF-2021-0071
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Transformation / Modification technique:
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direct DNA transfer system
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