detail view molecular characterisation GMO molecular characterization details

  • GMO:

    AquAdvantage Salmon
  • Alias:

  • UID:

  • Tradename:

    AquAdvantage
  • Company:

    AquaBounty Technologies Inc.
  • Developer:

    AquaBounty Technologies, Inc.
  • Species:

    Salmo salar
  • Traits:

    • Alteration in growth, development or product quality > Enhanced growth rate or yield

Description:

Southern blot analyses indicated the integration of the opAFP-GHc2 gene construct (EO-1alpha) at a single genomic locus. PCR and sequence analyses indicated that the construct had been reorganized. The insertion consists of the 3' segment (614 base pairs) of the ocean pout antifreeze promoter region (opAFP), the intact chinook salmon GH cDNA, the complete ocean pout antifreeze termination region and the first 1678 base pairs of the ocean pout antifreeze 5' region.

Sources: Yaskowiak ES, Shears MA, Agarwal-Mawal A, Fletcher GL (2006) Characterization and multi-generational stability of the growth hormone transgene (EO-1α) responsible for enhanced growth rates in Atlantic Salmon. Transgenic Research 15: 465–480

Freedom of Information Summary (FOI) Original New Animal Drug Application (NADA 141-454): opAFP-GHc2 rDNA construct in EO-1α lineage Atlantic salmon (AquAdvantage Salmon) Date of Approval: November 19, 2015

Links regarding to this GMO:

BCH Record ID: 104725 http://bch.cbd.int/database/record.shtml?documentid=104725, NADA 141-454 http://www.fda.gov/downloads/AnimalVeterinary/DevelopmentApprovalProcess/GeneticEngineering/GeneticallyEngineeredAnimals/UCM466215.pdf

Number of integration sites: 1

Transformation technique: microinjection

covers integration site(s)

insert only(s)

Name: insert_AquAdvantage Salmon
Comment: Source: Yaskowiak ES, Shears MA, Agarwal-Mawal A, Fletcher GL (2006) Characterization and multi-generational stability of the growth hormone transgene (EO-1α) responsible for enhanced growth rates in Atlantic Salmon. Transgenic Research 15: 465–480
Map:
First Reference Sequence:

vector(s)